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J Sci Food Agric 101:28462854

All qRTPCR experiments were performed in triplicate, and the relative mRNA expression levels were determined using the 2-Ct method

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Meanwhile, research using human brain organoid models has demonstrated that ferroptosis inhibitors (Ferrostatin-1) can block A pathology, reduce lipid peroxidation and restore iron storage function in AD organoids (86)

For instance, senescent M1 macrophages within atherosclerotic plaques release SASPs, increasing oxidative stress levels within plaques, leading to instability, rupture, and a heightened risk of AF (Vellasamy et al., 2022)