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Data from an open label pilot trial conducted to evaluate the feasibility and clinical and biological outcomes of a 2-week ITIS diet trial in RA patients showed an improvement of pain and other clinical scores

Invest Ophthalmol Vis Sci 47(5):213540

doi: 10.1016/j.eururo.2016.05.050 104 MasonMMPaiRKMastersonJMLokeshwarSDChuKYRamasamyR

The glutathione pathway may also supply glutamate when glia derived glutamine is blocked by MeAIB, which inhibits system A transporters

Furthermore any consideration of the protective action of UA in the central nervous system needs to be seen in the light of its well-established contributary role in the development of peripheral cardiovascular and metabolic diseases 2,3